An anthology of five short films exploring the impact of breast cancer on people’s lives is coming to Lifetime Monday, October 10 at 9p ET with five all-star women at the helm. They are Jennifer Aniston, Demi Moore, Alicia Keys, Patty Jenkins and  Penelope Spheeris.

Five highlights the shared experience of each short film’s title character in an interconnected story using humor and drama, and stars include Jeanne Tripplehorn, Patricia Clarkson, Rosario Dawson, David Eigenberg, Ginnifer Goodwin, Josh Holloway, Kathy Najimy, Jennifer Morrison, Tony Shaloub, Annie, Potts, Bob Newhart, Tracee Ellis Ross and Jeffrey Tambor amongst others.

At the premiere in NYC, when asked if she would like to continue directing, Jennifer Aniston answered, “that’s the plan.”